Paper by Tejas M. Bhatt and Dennis McCain. In this paper we discuss an efficient design flow from Matlab® to FPGA. Employing Matlab for algorithm research and as system level language allows efficient transition from algorithm development to implementation. We show that integrating Matlab with HDL design tools such as HDL designer® and Precision-C®, an efficient design flow, suitable for rapid prototyping, can be obtained. The design flow accelerates process of algorithm development and simplifies test-bench formulation and verification process. The overall development time thus can be significantly reduced. We elaborate on the advantages and disadvantages of the design flow. It will be shown that Matlab based design flow generates functional specifications that are useful for RTL development.